研  究  業  績



  

■ 2022 ■

          ☆  Milk fermented with mushrooms prevents stroke in the stroke-prone spontaneously hypertensive rats independently of blood pressure
             Zinat Mahal, Hiroyuki Matsuo, Hasan M Zahid, Yoshitomo Notsu, Hiroyuki Ohara, Kenji Okamoto and Toru Nabika
             J. Stroke Cerebrovasc. Dis., 31(5):106421 (2022)

  

■ 2021 ■

          ☆  Production of the antihypertensive peptide Tyr-Pro from milk using the white-rot fungus Peniophora sp. in submerged fermentation and a jar fermentor
             Kenji Okamoto, Ryosuke Ito, June Hayashi and Mizuki Tagawa
             Dairy, 2(3):452-461 (2021)

          ☆  Carboxylesterases for the hydrolysis of acetoacetate esters and their applications in terpenoid production using Escherichia coli
             Hisashi Harada, Daiki Senda, Takanori Shima and Chika Nakane
             Appl. Microbiol. Biotechnol., 105(14-15), 5821-5832 (2021)

          ☆  Direct ethanol production from xylan and acorn using the starch-fermenting basidiomycete fungus Phlebia acerina
             Kenji Okamoto, Takato Goda, Takeru Yamada and Masafumi Nagoshi
             Fermentation, 7(3):116 (2021)

          ☆  Pathway engineering using Escherichia coli to produce commercialized carotenoids
             Hisashi Harada
             Adv. Exp. Med. Biol., 1261, 191-199 (2021)

          ☆  Pathway engineering for high-yield production of lutein in Escherichia coli
             Miho Takemura, Akiko Kubo, Asuka watanabe, Hanayo Sakuno, Yuka Minobe, Takehiko Sahara, Masahiro Murata, Michihiro Araki, Hisashi Harada, Yoshinobu Terada, Katuro Yaoi, Kohji Ohdan, Norihiko Misawa
             Synthetic Biology, ysab012 (2021)

          ☆  Construction of transgenic Ipomoea obscura that exhibits new reddish leaf and flower colors due to introduction of β-carotene ketolase and hydroxylase genes
             Motoyasu Otani, Kosuke Kitayama, Hiroki Ishikuro, Jun-ichiro Hattan, Takeshi Maoka, Hisashi Harada, Yuko Shiotani, Akane Eguchi, Eiji Nitasaka, Norihiko Misawa
             Plant Biotechnol., 38, 219-226 (2021)

  

■ 2020 ■

          ☆  Production of antihypertensive peptide from milk by the brown rot fungus Neolentinus lepideus
             Kenji Okamoto, Sayo Kawamura, Mizuki Tagawa, Toshifumi Mizuta, Hasan M. Zahid and Toru Nabika
             Euro. Food Res. Technol., 246(9), 1773-1782 (2020)

          ☆  食用きのこ発酵乳由来のDPP-4阻害ペプチド
             岡本賢治
             アグリバイオ, 4(7), 54-55 (2020)

  

■ 2019 ■

          ☆  Ethanol production from cheese whey and expired milk by the brown rot fungus Neolentinus lepideus
             Kenji Okamoto, Saki Nakagawa, Ryuichi Kanawaku and Sayo Kawamura
             Fermentation, 5(2):49 (2019)

  

■ 2018 ■

          ☆  バイオ実験を安全に行うために,日本生物工学会編(分担執筆)
             岡本賢治
             化学同人 (2018)

  

■ 2017 ■

          ☆  The formation and sequestration of nonendogenous ketocarotenoids in transgenic Nicotiana glauca
             Cara L. Mortimer, Norihiko Misawa, Laura Perez-Fons, Francesca P. Robertson, Hisashi Harada, Peter M. Bramley and Paul D. Fraser
             Plant Physiol., 173(3), 1617-1635 (2017)

          ☆  Isolation of a Peniophora strain capable of producing ethanol from starch and kitchen waste
             Kenji Okamoto, Motoki Yoneda and Toko Fumioka
             Ferment. Technol., 6:1 (2017)

  

■ 2016 ■

          ☆  Structural analysis and physiological properties of exopolysaccharides secreted by a newly isolated Pseudomonas stuzeri BL58 under alkaline conditions
             Hiroyuki Yamada, Shinichi Yoshida, Koji Nozaki, Tomoyuki Doi, Hiroko Nkakamura and Hideshi Yanase
             J. Biotecnol. Biomater., 6:4 (2016)

          ☆  Peroxidase-catalyzed oxyfunctionalization reactions promote by the complete oxidation of methanol
             Yan Ni, Elena Fernandez-Fueyo, Alvaro Gomez Baraibar, Renee Ullrich, Martin Hofrichter, Hideshi Yanase, Miguel Alcalde, Willem J. H. van Berkel and Frank Hollmanna
             Angrew. Chem. Int. Ed., 55(2), 798-801 (2016)

  

■ 2015 ■

          ☆  Complete enzymatic oxidation of methanol to carbon dioxide: towards more eco-efficient regeneration system for reduced nicotinamide cofactors, (VIP: Very Important Publication)
             Selin Kara, Joerg H. Schrittwieser, Serena Gargiulo, Yan Ni, Hideshi Yanase, Diederik J. Opperman, Willem J. H. van Berkel and Frank Hollmanna
             Adv. Synth. Catal., 357(8), 1687-1691 (2015)

          ☆  組換え微生物によるカロテノイド生産
             原田尚志,小島 基,鈴木宗典,金本浩介
             生物工学会誌, 93(7), 397-402 (2015)

          ☆  高速発酵細菌の利用による木質バイオマスの高効率同時糖化並行発酵
             簗瀬英司,渡辺隆司
             バイオインダストリー, 32(5), 10-17 (2015)

  

■ 2014 ■

          ☆  きのこの香り
             岡本賢治
             菌蕈, 60(6), 13-19 (2014)

          ☆  Construction of transplastomic lettuce (Lactuca sativa) dominantly producing astaxanthin fatty acid esters and detailed chemical analysis of generated carotenoids
             Hisashi Harada, Takashi Maoka, Ayako Osawa, Jun-ichiro Hattan, Hirosuke Kanamoto, Kazutoshi Shindo, Toshihiko Otomatsu and Norihiko Misawa
             Transgenic Res., 23(2), 303-315 (2014)

          ☆  Bioconversion of xylose, hexoses and biomass to ethanol by a new isolate of the white rot basidiomycete Trametes versicolor
             Kenji Okamoto, Atsushi Uchii, Ryuichi Kanawaku and Hideshi Yanase
             SpringerPlus, 3:121 (2014)

          ☆  セルロース系バイオエタノール生産のための発酵細菌のメタボリックエンジニアリング
             簗瀬英司
             バイオサイエンスとインダストリー, 72(1), 24-28 (2014)

  

■ 2013 ■

          ☆  菌類の事典(分担執筆),日本菌学会編
             バイオエタノール
             岡本賢治
             朝倉書店, pp.535-537 (2013)

          ☆  Direct ethanol production from cellulosic materials by Zymobacter palmae carrying Cellulomonas endoglucanase and Rumincoccus β-glucosidase genes
             Motoki Kojima, Kenji Okamoto and Hideshi Yanase
             Appl. Microbiol. Biotechnol., 97(11), 5137-5147 (2013)

          ☆  菌類きのこ遺伝資源-発掘と応用-(分担執筆),GCOE「持続性社会構築に向けた菌類きのこ資源活用」編集委員会編
             菌類きのこによるバイオマスからの直接的エタノール生産
             岡本賢治,簗瀬英司
             丸善プラネット, pp.154-164 (2013)

  

■ 2012 ■

          ☆  C5・C6糖発酵担子菌によるバイオマスからの直接的エタノール生産
             岡本賢治
             日本菌学会報, 53(2), 63-70 (2012)

          ☆  ひらく、ひらく「バイオの世界」14歳からの生物工学入門,日本生物工学会編(分担執筆)
             岡本賢治
             化学同人 (2012)

          ☆  Expression and surface display of Cellulomonas endglucanase in the ethanologenic bacterium Zymobacter palmae
             Motoki Kojima, Tomohiro Akahoshi, Kenji Okamoto and Hideshi Yanase
             Appl. Microbiol. Biotechnol., 96(4), 1093-1104 (2012)

          ☆  Ethanol production from wood hydrolysate using genetically engineered Zymomonas mobilis
             Hideshi Yanase, Hitoshi Miyawaki, Mitsugu Sakurai, Akinori Kawakami, Mari Matsumoto, Toshio Haga, Motoki Kojima and Kenji Okamoto
             Appl. Microbiol. Biotechnol., 94(6), 1667-1678 (2012)

          ☆  Efficient xylose fermentation by the brown rot fungus Neolentinus lepideus
             Kenji Okamoto, Ryuichi Kanawaku, Masaru Masumoto and Hideshi Yanase
             Enzyme Microb. Technol., 50(2), 96-100 (2012)

  

■ 2011 ■

          ☆  Characterization of two acidic β-glucosidases and ethanol fermentation in the brown rot fungus Fomitopsis palustris
             Kenji Okamoto, Yuko Sugita, Natsumi Nishikori, Yasuyuki Nitta and Hideshi Yanase
             Enzyme Microb. Technol., 48(4-5), 359-364 (2011)

          ☆  Direct ethanol production from starch, wheat bran and rice straw by the white rot fungus Trametes hirsuta
             Kenji Okamoto, Yasuyuki Nitta, Nitaro Maekawa and Hideshi Yanase
             Enzyme Microb. Technol., 48(3), 273-277 (2011)

  

■ 2010 ■

          ☆  マイクロ波ソルボリシスと高速発酵細菌を用いる高効率バイオエタノール生産システム
             渡辺隆司,簗瀬英司
             クリーンエネルギー, 19(12), 1-6 (2010)

          ☆  Production of ethanol by the white-rot basidiomycetes Peniophora cinerea and Trametes suaveolens
             Kenji Okamoto, Koji Imashiro, Yuya Akizawa, Asako Onimura, Motoki Yoneda, Yasuyuki Nitta, Nitaro Maekawa and Hideshi Yanase
             Biotechnol. Lett., 32(7), 909-913 (2010)

          ☆  セルロース系バイオエタノール製造技術(分担執筆),監修:近藤昭彦、植田充美
             新規発酵細菌によるバイオエタノール連続並行発酵プロセスの構築
             簗瀬英司
             エヌ・ティー・エス, pp.251-262 (2010)

          ☆  7-Ketocholesterol catabolism by Rhodococcus jostii RHA1
             Jacques Mathieu, William W. Mohn, Lindsay D. Eltis, Justin LeBlanc, Gord Stewart, Carola Dresen, Kenji Okamoto and Pedro J.J. Alvarez
             Appl. Environ. Microbiol., 76(1), 352-355 (2010)

          ☆  次世代バイオエタノール生産の技術革新と事業展開(分担執筆),監修:鮫島正浩
             担子菌・マイクロ波照射前処理と高速発酵細菌を用いる高効率バイオエタノール生産システム
             渡辺隆司,簗瀬英司
             フロンティア出版, pp.287-294 (2010)

  

■ 2009 〜 2002 ■

          ☆  The genomic structure of thermus bacteriophage φIN93
             Isao Matsushita, Hideshi Yanase
             J. Biochem., 146(6), 775-785 (2009)

          ☆  A novel insersion sequence transposed to thermophilic bacteriophage φIN93
             Isao Matsushita, Hideshi Yanase
             J. Biochem., 146(6), 797-803 (2009)

          ☆  産業用酵素の応用技術と最新動向(分担執筆),監修:井上國世
             多機能転移酵素による新規配糖体の合成
             簗瀬英司
             シーエムシー出版, pp.308-319 (2009)

          ☆  スイートソルガムの搾汁に関する研究
             孫孝政,山名伸樹,簗瀬英司
             農業機械学会誌, 71(4), 69-73 (2009)

          ☆  A novel thermophilic lysozyme from bacteriophage φIN93
             Isao Matsushita, Hideshi Yanase
             Biochem. Biophys. Res. Commun., 377, 89-92 (2008)

          ☆  キノコによるエタノール・キシリトールの効率的生産
             岡本賢治
             New Food Industry, 50(6), 6-10 (2008)

          ☆  Decrease in hydrogen sulfide content during the final stage of beer fermentation due to involvement of
             yeast and not carbon dioxide gas purging
             Kaneo Oka, Teruhiko Hayashi, Nobuya Matsumoto, and Hideshi Yanase
             J. Biosci. Bioeng., 106(3), 253-257 (2008)

          ☆  バイオリファイナリー技術の工業最前線−自動車用バイオ燃料の技術開発−(分担執筆),監修:湯川英明
             ザイモモナス菌によるエタノール発酵
             簗瀬英司
             シーエムシー出版, pp.246-262 (2008)

          ☆  バイオ液体燃料(分担執筆)
             木質系バイオマスからの高速度バイオエタノール製造技術
             簗瀬英司
             エヌ・ティー・エス, pp.115-125 (2007)

          ☆  Stabilized production of highly concentrated bioethanol from fermentation broths by Zymomonas mobilis
             by pervaporation using silcone rubber coated silicalite membrane
             T. Ikegami, H. Negishi, H. Yanase, and K. Sakaki
             J. Chem. Technol. Biotechnol., 82, 745-751 (2007)

          ☆  Genetic Engineering of Zymobacter palmae for production of ethanol from xylose
             Hideshi Yanase, Dai Sato, Keiko Yamamoto, Saori Matsuda, Sho Yamamoto, and Kenji Okamoto
             Appl. Environ. Microbiol., 73(8), 2592-2599 (2007)

          ☆  Purification and characterization of extracellular 1,2-α-L-fucosidase from Bacillus cereus
             Toyokazu Miura, Kenji Okamoto, and Hideshi Yanase
             J. Biosci. Bioeng., 99(6), 625-635 (2006)

          ☆  Characterization of arylsulfatase formed by depressed synthesis Citrobacter brakii
             Toyokazu Miura, Kenji Okamoto, and Hideshi Yanase
             Biosci. Biotechnol. Biochem., 70(6), 1509-1512 (2005)

          ☆  エコバイオエネルギーの最前線−ゼロエミッション型社会を目指して−(分担執筆)
             新規エタノール発酵細菌ザイモバクターの育種
             簗瀬英司
             シーエムシー出版, pp.000-000 (2005)

          ☆  Ethanol production from cellulosic materials by genetically engineered Zymomonas mobilis
             Hideshi Yanase, Koji Nozaki, and Kenji Okamoto
             Biotechnol. Lett., 27(4), 259-263 (2005)

          ☆  Ethanol production from cellobiose by Zymomobacter palmae carrying Ruminococcus albus β-glucosidase gene
             Hideshi Yanase, Keiko Yamamoto, Dai Sato, and Kenji Okamoto
             J. Biotechnol., 118(1), 35-43 (2005)

          ☆  Cyanide fishing and cyanide detection on coaral reef fish using chemical tests and biosensors
             K. K. W. Mak, H. Yanase, and R. Renneberg
             Biosensors and Bioelectronics, 20, 2581-2593 (2005)

          ☆  Application of cyanide hydrolase from Klebsiella sp. In a biosensor system for the detection of low-level cyanide
             K. K. W. Mak, A. W. C. Law, S. Tokuda, H. Yanase, and R. Renneberg
             Appl. Microbiol. Biotechnol., 67, 631-636 (2005)

          ☆  Cloning and characterization of a laccase gene from the white-rot basidiomycete Pleurotus ostreatus
             Kenji Okamoto, Yasuhiro Ito, Ichirou Shigematsu, Sonoe Ochiai Yanagi, and Hideshi Yanase
             Mycoscience, 44(1), 11-17 (2003)

          ☆  Isolation and application of a styrene-degrading strain of Pseudomonas putida to biofiltration
             Kenji Okamoto, Maki Izawa, and Hideshi Yanase
             J. Biosci. Bioeng, 95(6), 633-636 (2003)

          ☆  E10,ED15とメタボリックエンジニアリング
             簗瀬英司
             化学, 化学同人, 58(12), 51-53 (2003)

          ☆  Effects of GroESL coexpression on the folding of nicotinoprotein formaldehyde dismutase from
             Pseudomonas putida F61
             Hideshi Yanase, Keishi Moriya, Norihiko Mukai, Yasushi Kawata, Kenji Okamoto, and Nobuo Kato
             Biosci. Biotechnol. Biochem., 66(1), 85-91 (2002)

          ☆  Biosynthesis of p-anisaldehyde by the white-rot basidiomycete Pleurotus ostreatus
             Kenji Okamoto, Shinji Narayama, Ichirou Shigematsu, Akihisa Katsuo, and Hideshi Yanase
             J. Biosci. Bioeng., 93(2), 207-210 (2002)

          ☆  Characterization of Membrane Bioreactor for Dry Wine Production
             Masamitsu Takaya, Nobuya Matsumoto, and Hideshi Yanase
             J. Biosci. Bioeng., 93(2), 240-244 (2002)

          ☆  Removal of acrylonitrile and styrene by a packed tower biofilter   
             Kenji Okamoto, Maki Izawa, and Hideshi Yanase
             Proceedings of the Air & Waste Management Association's 95th Conference & Exhibition,
             June 23-27, 2002, Baltimore, MD, USA, Paper 42851

          ☆  Production of γ-lactones by the brown-rot basidiomycete Piptoporus soloniensis
             Kenji Okamoto, Mieko Chimori, Fumi Iwanaga, Tsutomu Hattori, and Hideshi Yanase
             J. Biosci. Bioeng., 94(2), 182-185 (2002)

          ☆  Aryl alcohol oxidases from the white-rot basidiomycete Pleurotus ostreatus
             Kenji Okamoto and Hideshi Yanase
             Mycoscience, 43(5), 391-395 (2002)

          ☆  Identification of functionally important amino acid residues in Zymomonas mobilis levansucrase
             Hideshi Yanase, Masahiro Maeda, Eigo Hagiwara, Hiroyuki Yagi, Kenji Taniguchi, Kenji Okamoto
             J. Biochem. 132, 565-572 (2002)

          ☆  生物工学実験書−改訂版−,日本生物工学会編(分担執筆)
             クロマトグラフィー
             簗瀬英司,岡本賢治
             培風館, pp.49-52 (2002)

          ☆  廃紙・廃材をエタノールに変換する
             簗瀬英司
             化学と生物, 培風館, 40(10), 565-572 (2002)

  



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