最近の主な論文

 

Hino, T., Matsumoto, Y., Nagano, S., Sugimoto, H., Fukumori, Y., Murata, T., Iwata, S., *Shiro, Y. “Structural Basis of Biological N2O Generation by Bacterial Nitric Oxide Reductase” Science 330, 1666-1670, 2010


  • Wang, Y., Chen, H., Makino, M., Shiro, Y., Nagano, S.,*, Asamizu, S., Onaka, H.,* and Sason, S.* Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP: The Biological Role of Water Molecules, J. Am. Chem. Soc. 131, 6748-6762, 2009

 

Wang, Y., Hirao, H., Chen, H., Onaka, H., Nagano, S., and Shaik, S.* Electron transfer activation of chromopyrrolic acid by cytochrome P450 En route to the formation of an antitumor indolocarbazole derivative: Theory supports experiment, J. Am. Chem. Soc. 130, 7170-7171, 2008

 

Hirano, S., Asamizu, S., Onaka, H.*, Shiro, Y., and Nagano, S.* Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein, J. Biol. Chem. 283, 6459-6466, 2008

 

Makino, M., Sugimoto, H., Shiro, Y., Asamizu, S., Onaka, H.*, and Nagano, S.* Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton, Proc. Natl. Acad. Sci. USA 104, 11591-11596, 2007

 

Nagano, S.*, and Poulos, T. L.* Crystallographic study on the dioxygen complex of wild-type and mutant cytochrome P450cam - Implications for the dioxygen activation mechanism, J. Biol. Chem. 280, 31659-31663, 2005 Selected as a Paper of the Week and Journal Cover

 

Nagano, S.*, Cupp-Vickery, J. R., and Poulos, T. L.* Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T - Investigation of the proton transfer system in P450eryF, J. Biol. Chem. 280, 22102-22107, 2005

 

Nagano, S., Tosha, T., Ishimori, K., Morishima, I., and Poulos, T. L.* Crystal structure of the cytochrome P450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding, J. Biol. Chem. 279, 42844-42849, 2004